The Stooges are janitors working at a space center who accidentally blast off to Venus. They encounter a talking unicorn, a giant fire breathing tarantula, and an alien computer who has destroyed all human life on the planet and creates three evil duplicates of the Stooges. When the boys return home triumphant, they are given a hero's welcome.

Landed on the moon, Capt. John Anderson and his fellow astronauts quickly find their mission threatened – first by the disappearance of two team members, then by a troubling interaction with aliens who appear to be living within the moon itself. The aliens have weapons that could plunge parts of Earth into another ice age, and they're aiming for the United States.

A team of agents is sent to a secret location in South America to investigate reports that a group of Nazis actually rescued Adolf Hitler at the end of the war and are hiding him.