In every man there lies a woman who can be awakened. The prohibited book De Serpentis Munere. Alchemical formulae able to change male DNA in female. Mysterious radioactive water. A biologist and a Vatican priest in search of the truth.

Rosaria is a young mother, wife of Tommasino Malarazza, downfallen boss of a famous Mafia family in Catania. Forced to marry him because she was pregnant, Rosaria is humiliated everyday by a violent husband, who spends his days drinking and gambling. The woman lives in fear and keeps her head down to protect her son Antonino. She can only rely on her queer brother Franco.