A crazed janitor catches two people having sex in the office and murder ensues.

Tully Jr. and Earl live on their father's Nebraska ranch, proud and independent to a fault. While the shy, reclusive Earl spends his free time watching movies, the cockier Tully works his way through a succession of short-term affairs and an off-again, on-again relationship with April, a stripper in town. When their childhood friend Ella returns to town to start a veterinary practice, however, Tully falls for her — although the townsfolk have their doubts that he could ever commit to one woman.

Lionel is a custodian that longs for more. Bombarded with daily disrespect and insults from his co-workers, Lionel sets on a path of revenge and begins to brutally murder everyone in his path.

Izzy is raising her younger brother, Kevin, by herself. Their parents are deceased and her older brother, Rusty, is away in the Marines. When Izzy learns that her little brother is being bullied at school, she does what any unstable, psychopathic, homicidal sister would do.

In the rail yards of Queens, contractors repair and rebuild the city's subway cars. These contracts are lucrative, so graft and corruption are rife. When Leo Handler gets out of prison, he finds his aunt married to Frank Olchin, one of the big contractors; he's battling with a minority-owned firm for contracts.

Phil and Anna are a young, married couple, who begin to suspect one other of an affair. When a shady private investigator gets involved in their relationship, things begin to spin out of control, in this turn-of-the-millennium thriller.