13-year-old Felix Xaba dreams of becoming a saxophonist like his late father, but his mother Lindiwe thinks jazz is the devil's music. When Felix leaves his township friends to take up a scholarship for grade eight at an elitist private school, he defies his mother and turns to two aging members of his father's old band to help him prepare for the school jazz concert.

Set in Cape Town, South Africa Mama Jack is the story of Jack Theron, an ordinary person working on a film set. However, his movie producer boss hates him and wants to remove him from the production of the film. In a bid to get rid of Jack, the producer spikes his drink with a drug at a glamorous function, and before long Jack has got himself on the wrong side of the law. While on the run, Jack turns to his friend, a make-up artist, who turns him into "Mama Bolo". Mama Bolo soon finds “herself” employed by the producer’s fiancée, Angela. A series of deceptions and misunderstandings pile up and comic mayhem ensues with Jack Theron becoming another character, Doctor Donald, a tramp from Scotland.