Haruni screams in pain of being possessed by a devil. As well as being in pain it also tends to hurt her. Haruni's younger brother, Hanum, has glaucoma. Dr. Ahmad, who was treating Hanum, heard Haruni's story. He then treated Haruni during the night of the recitation. Haruni's body spasmed violently and managed to release all the bonds on her body and jumped into the window of the second floor of the house. Ahmad suspects that Haruni has a connection with the suicide case. The body of the person who killed himself also mastered the demon flowing in Haruni's blood. Ahmad and a police friend helped Haruni with a problem, looking for data on people who committed suicide, and expelling the evil spirit from Haruni's body.

In 1920s Dutch East Indies, Giandra, a young doctor from STOVIA, reads about Layla—a girl shackled in a remote village as a "cure" for mental illness. Disturbed, he travels to Karuhun, where tradition and mysticism prevail over science. Guided by journalist Rikke, who warns him with three words—Culture. Mysticism. Superstition.—Giandra must confront a clash between modern medicine and ancestral belief.