A Spanish theatre company is rehearsing Shakespeare in the original style using young men to play the women's roles. Complicating their endeavors is the previously straight director's infatuation the new young man whose charming everyone except the slightly older young man who he's replacing. When the young man on the way out decides to settle the score with the young man on the way up, he draws on what he's learned in the theatre. Enter Iago.

Located in Madrid's Plaza del Sol, Km. 0 is the point from which all distances in Spain are measured from the capital. In Km. 0, it is also the meeting point for a gallery of characters. Bored, affluent housewife Marga meets up with gigolo Miguel, who co-habitates with gay Benjamin. Sergio, a soon-to-be-married office clerk who can't wait to lose his virginity, makes the acquaintance of prostitute Tatiana, while gay dancer Bruno meets Maximo. Meanwhile, wannabe director Pedro arranges to meet up with Silvia, an actress who wants to work in musicals directed by Gerardo, and bartender Mario is caught between Amor, who wants to marry him, and her little sister Roma, who is truly in love with him.

Miguel is a child that loves her neighbour Ángela and enjoy working in the pastry-cook's shop of his family. He don't tell Ángela his feelings, and when they grow Ángela marry with another man and has two sons with him, but she continues her friendship with Miguel.However, she will not be happy with her husband and will return to the town with Miguel, and they will show their true feelings.

Sarah is getting ready to go out for dinner. Suddenly she feels that she's not alone at home.