In search of a miracle, an American woman embarks on a journey to the Peruvian Amazon and finds hope in a community, through rituals involving an ancient psychedelic plant known as ayahuasca. With her perception forever altered, she forges a bond with a young indigenous shaman undergoing a crisis of his own, and a motley crew of psychonauts seeking transcendence, companionship, and the meaning of life and death.

Mr. Devereaux is a powerful man. A man who handles billions of dollars every day. A man who controls the economic fate of nations. A man driven by a frenzied and unbridled sexual hunger. A man who dreamed of saving the world and who cannot save himself. A terrified man. A lost man.