Based on a true story, Sam Chuk exposes 7 teenagers in a neighborhood called Sam Chuk, whose lives are entangled with troubles and devastated by using drugs. Their local teacher is seriously concerned the drugs problem and begins to cope with them by giving them a chance to prove themselves.

Inspired by the Bang Rajan warriors who did not give up hope in their battle against the Burmese invaders, a group of villagers form a guerrilla unit to battle their enemies.