Maos Sangrentas translates to Bloody Hands in English, and that's just what this gruesome Brazilian melodrama delivers. The story begins when a gang of dangerous convicts escape from a penal colony. With the police in hot pursuit, the escapees cut a gory swath through the countryside. As his comrades are killed off one by one, the leader of the group descends into gibbering madness. In contrast to this, a subplot develops involving the least dangerous of the escapees, who murdered his wife in a peak of self-righteous rage and is now seriously in doubt about the wisdom of his deed. Principal scenes reworked in 1962 to make the film The Violent and the Damned (q.v.).

When chain gang prisoners attack their guards, some of the hardened criminals escape Brazil's infamous Anchieta Prison amidst all the pick-ax carnage. The government dispatches a machine-gun squad to round up the fugitives, who have fled by foot and boat and now have begun to turn on each other.