High school senior Morgan's older sister and good friends, Jackie, Vic, and Tiff, comfort her when her senior picture day takes a turn for the worse thanks to an old elementary besty and current rival, Maria Sanchez. After successfully seeing through the perfect plot for revenge, the four young ladies find a lucrative business venture to be made of what was supposed to be a one-time payback to put Maria in her place. Things are going great until their endeavors lead them barking up the wrong tree – only in this case, the tree bites back.

After witnessing a harrowing murder, three strangers are forced to rely on each other as they navigate a chaotic nocturnal odyssey.