Edo is an 18 years old boy with fast-progressing alopecia, which he wants to cure before his boyfriend returns from his year abroad. The drops he takes begin to transform something in his body. However, also his boyfriend seems to have undergone a change...

Sìgaretta follows a day in the life of three outcast friends, Sì, Gar and Etta, who decide to throw a house party to impress their peers.