One day in Palermo and in the life of young boy Toto who is madly in love with the beautiful teenager Lina.

2052. A car is driving on an empty road during the night. Inside there's a Middle Eastern family and the daughter's Italian boyfriend. A policeman follows the car, and then decides to stop it and ask for papers.

In 1920s Bagheria, Giuseppe 'Peppino' Torrenuova works as a shepherd to financially help his poor family. Over the next fifty years, Giuseppe's life, as well as the life of the village, is observed. Giuseppe grows up, joins the Communist Party, marries a local girl, has children, and forges a political career for himself.

Vigàta, Sicily, Italy, 1880. Shortly after the return to the village of Fofò La Matina, pharmacist and son of the late Santo La Matina, jealous guardian of the secrets of certain miraculous plants, the noble Peluso family is ravaged by a series of mysterious deaths…

Although Pippo Genuardi seems to have cleared his mind by marrying Taninè Schilirò, daughter of the richest man in Vigàta, he is in fact someone who is not satisfied with his life…

Andrea Licari, a Tunisian of Italian descent now 60 years of age, has become an accomplished author, college professor and a leading thinker in Rome. Today, Andrea finds himself facing the most challenging time of his life.