65 year old doctor Pierfrancesco works as a night-shift medical guard. He’s a grumpy man, full of aches and pains and is very rough with his patients. One night, he’s involved in a road collision with 30 year old delivery man Mario. While uninjured, Mario's bicycle is destroyed, and Pierfrancesco's sciatica flares up, making it impossible for him to drive. With both of their jobs in jeopardy, the doctor has an idea that could help them both: “remotely guided” by Pierfrancesco via wireless headset, Mario will visit his patients, and they’ll also carry out Mario’s delivery in Pierfrancesco’s car. After a range of daring (mis)adventures, they will learn to support each other, and the night will end with their lives both changed for the better.

Heartbroken that their children no longer want to spend time with them, two parents fake an inheritance to bring the family together for Christmas.

The destinies of two families are irrevocably tied together after a cyclist is hit off the road by a jeep in the night before Christmas Eve.

Two different men living in Milan lose their job at the same time. They will become a funny couple of thieves thanks to the poorest of them that was already a thief.

Enrico, Fabrizio, and Stefano are three lifelong friends and colleagues who share left-wing political ideals. They run a small production company, juggling commercials and wedding shoots, but hope to return to making social-themed documentaries. One day, they receive a financially attractive offer that seems to meet their expectations. Unfortunately, the deal has unethical implications.

Mr. Imbruttito, a leading executive of a large multinational, lives the routine in his hectic Milan. Breaking this balance is Brusini, an eccentric entrepreneur at the head of an economic empire, who for an absurd reason blows up what for the Brutito is the business of life. For the first time, the Ugly one feels the pinch, falls into depression, can no longer find a reason to wake up in the morning. The turning point comes from Brera, a longtime friend, who proposes to the Bruttito the purchase of a Chiringuito in Sardinia, to do business in flip-flops and finally be able to say: "I quit everything and open a chiringuito!"