When two ecologists break-in the laboratory of Dr. Belmont, they find a box with a subject and they decide to set the experiment free in the woods. During the transportation, the box opens and releases the mutant Tasmanian Devil that devours the two activists and escapes to the woods. Meanwhile, Dr. Belmont's son Hunter travels in a van with four friends to film a horror movie in the cemetery in the woods, while Belmont and his associate Dr. Christine Kollar seek their deadly experiment called Precious.

A selection of news reports chronicling the outbreak of the zombie epidemic experienced in Dawn of the Dead (2004).

When Cherokee (Elizabeth Hayden Grace), a cocktail waitress in a local topless bar, wants to become a topless dancer to make more money, she falls in with three mysterious and beautiful strippers who happen to be vampires. The queen vampire, Elyse (Aime Wolf), finds Cherokee a tasty morsel.