Martha is a single woman who becomes pregnant and commits suicide after giving birth to a pair of twins, Jessica and Angelica, who are adopted separately. Years later, Angelica becomes a lawyer working for the mafia. Jessica, who was adopted by a prostitute, has become a criminal and is now arrested for the murder of her husband. In prison she tries to be friends with the director without success and she has to pay her sentence.

Dr. Vlidi Mazo suffers from a terminal illness that ossifies his skin. Inspired by his own blood, a tooth, a fish scale and the skin of a grape, he sets out to create a cure to save himself.