The lives of different sets of people residing in Kasimedu change irreversibly overnight after an unforeseen incident. What happens next and how does karma play a major role in their lives?

Vikram, an inspector from Kutralam, stumbles upon a string of bizarre accidents that all seem to follow a strange pattern. But as he digs deeper, he uncovers a medical crime that sends shockwaves through the place.

A mysterious illness declared as dumb flu spreads in a quaint hill station forcing the town's residents from speaking. Will the problems in the place increase due to this or will it lead to better communication?

Shiva and Indu are city-based students,who love each other. However, their love is strongly opposed by the latter’s parents. They're given a handwritten book titled "Pathinaaru" (Sixteen) by Indhu's mother to read. The book depicts a real-life story about two village teenagers Gopi and Ilavarasi, and their romance as they step into adolescence. Facing opposition from her affluent family, the gutsy Ilavarasi takes some bold unconventional steps, which backfires on her. The story of unrequited love and betrayal leaves Indu in a dilemma and she prepares to go with her family’s desires. But Siva is not ready to give up Indu and sets out to do his own investigation to get to the bottom of what ultimately happened to Gopi and Ilavarasi.

Three brothers return to their native village to mend the relationship between their estranged father and his sisters. However, to unite the family, the brothers are told to marry their cousins.

A restaurant owner experiences mysterious activities in his kitchen, only to discover a connection with the ghost haunting his place.

Jai and Neha, eloping to Hyderabad to get married, offer lift to a stranger on the highway not realizing that he is a murderous psychopath who has escaped from a mental asylum.

Two school students find their classmate murdered in their classroom and decide to track down the killer.

Detective Kaniyan Poonkundran is hungry for a challenging case to investigate and the mystery of a murdered dog leads to a rival who could be the match for him.