Sim Sala Bim is about a funny chain of events experienced by İsmail Dümbüllü upon his arrival in Istanbul. He has a job at a theater company, but the manager fires him for slacking off at work. He sets out for Istanbul with plans to meet with his girlfriend Aysel and arrives in the city following a rather eventful journey. Accompanied by his friend Rasih, Dümbüllü goes in and out of jobs while tracking down his girlfriend in the big city. Just as everything seems to go against him, a genie in his dream gives him a magic wand which will prove to be highly useful.

As soon as Ali is released from prison, he rushes to his friend Selim's side. In the evening, they go to Viran Kazım's tavern. The tavern owner's daughter Zehra is also there. Ali and Zehra fall in love at first sight. Ali begins making plans to start a new life with Zehra. However, Çamur Süleyman, the troublemaker of the neighborhood, has no intention of letting Zehra go.

The events that happened to Recep and Saban who came to Istanbul for the first time.