Sean Astin

Randall P. McDuff / Josiah (voice)

Pamela Hayden

Sublimity Jill / Daughter #2 (voice)

Scott Lawrence

Lewis Clark Jefferson / Cowpoke #3 (voice)

Maurice LaMarche

Bumpy Snits / Ferryman #1 / Cowpoke #2 (voice)

Carolyn Lawrence

Ornery Sue / Wagonmaster's Wife / Daughter #3 (voice)

Craig Bartlett

Romeo Jones / Ferryman #2 / Cheyenne #1 (voice)

Andrea Bowen

Billie Bartley / Manifest Destiny (voice)

Josh Hutcherson

Toad E. Bartley (voice)

Dan Conroy

Wagonmaster / Pioneer #1 / Cowpoke #1 (voice)

Danny Mann

Three-Eyed Jack / Wall-Eyed Tom (voice)